A non-clinical and clinical IUCLID database dashboard for pharmaceuticals​

This dashboard visualises the US FDA toxicity data published on IUCLID, containing preclinical animal studies and human data on approved pharmaceuticals. The data have been migrated to OECD harmonised templates (OHT) and complemented by the PaCCO ontology. Reference: Evangelisti et al. A non-clinical and clinical IUCLID database for 530 pharmaceuticals (part I): Methodological aspects of its development. Regulatory Toxicology and Pharmacology, 2023, 105416.

530

New drug applications (NDAs)

6021

Non clinical studies

113477

Annotated non-clinical effects

3414

Unique ontological terms

566

Reference substances

15652

Adverse reactions from standard product labels (SPLs)​

Drug data​

Molecolar weight distribution
Most common pharmacological class​
Browse NDAs
Name
NDA016608-carbamazepine
NDA017558-glycopyrrolate
NDA017970-tamoxifen citrate
NDA018998-enalapril maleate
NDA019386-esmolol hydrochloride
NDA019922-fenoldopam mesylate
More details...

Non-clinical data (animal)

Pharmacological study type
Species distribution
Effect Basis distribution
RDT route of administration
RDT study endpoint

Non-clinical data (human)

https://toxicity-dataviz.innovamol.com/ https://toxicity-dataviz.innovamol.com/